Characterization of B cells in lupus erythematosus skin biopsies in the context of different immune cell infiltration patterns
Cutaneous lesions in lupus erythematosus (LE) subtypes are heterogenous.In line with the heterogeneity of the clinical presentation, the underlying lesional inflammation in LE skin samples is defined by different immune cell infiltrates.Pathophysiologically, lesional inflammation is driven by autoreactive cytotoxic T cells, targeting keratinocytes;